★★★★★

4.8 · 1,200+ member reviews

HSA & FSA eligible

MOTS-c (Injection)

A peptide encoded by your mitochondria rather than your nuclear DNA. Prescribed and dosed by a licensed provider around your history and how you respond.

Plans as low as

$69

/month

$149

Save 54%

Free shipping

No insurance required

Prescribed by US licensed providers

Dosed to you, not to an average

Coming Soon Important safety information

Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. Prescription required.

What is MOTS-c used for?

Metabolic health. The research looks at how cells handle glucose and energy, which is why it comes up around insulin sensitivity and aging rather than injury.

Why do people call MOTS-c an exercise molecule?

In mice, it acts on a metabolic pathway that exercise also switches on. It's not a replacement for training, and we won't sell it as one.

Where does my MOTS-c come from?

A state licensed US compounding pharmacy prepares it for you, and every batch is third party tested for purity and potency. Compounded medications are not approved or evaluated by the FDA for safety, effectiveness or quality. Compounding pharmacies are licensed and inspected by state Boards of Pharmacy and are highly regulated. A prescription is required.

How it works

From first question to front door.

What you get with Science & Co

A treatment plan with dose adjustments when clinically appropriate, a quick online assessment reviewed by a licensed provider, secure messaging and scheduled check ins with your care team, and medication shipped cold packed to your door. Every plan includes supplies, shipping and ongoing clinical monitoring.

How to take it

A once weekly injection you give yourself, on the same day each week unless your provider tells you otherwise. You start low and step up on a set schedule, which gives your body time to adjust and keeps side effects manageable.

Potential side effects

The most common side effects are nausea, constipation and diarrhoea, and they usually settle as your body adjusts to each step up in dose. Your provider reviews how you are doing at every check in and can slow the schedule down if you need it.

How does Science & Co ensure quality and safety?

We work only with state licensed US compounding pharmacies. Every batch is third party tested for purity and potency, and you can request a Certificate of Analysis for your prescription at any time.

How it works

From first question to front door.

Four steps from your first question to your first delivery. No clinic visit, no insurance required.

Coming Soon

Member choosing healthy aging as their goal in the Science and Co questionnaire

Step 01

Take the quiz

A few questions about your health history, medications and goals. Five minutes, all online.

Step 02

Provider review

A US licensed provider reads your history and prescribes only if it is right for you.

Science and Co medication shipment being unboxed at home

Step 03

Free delivery

Prepared by a licensed US pharmacy and shipped free to your door, cold packed when needed.

Member messaging the Science and Co care team about energy on their current dose

Step 04

24/7 support

Message your care team any time, with regular check ins and dose adjustments as you go.

Inside MOTS-c

Where MOTS-c
does its work

A peptide your mitochondria make, not your nuclear DNA. Here is where it shows up.

Metabolism

Glucose handling
Insulin research
Fat metabolism
Metabolic health

Exercise

AMPK pathway
Endurance research
Muscle energy
Pairs with training

Mitochondria

Mitochondrial DNA
Cell energy
One of eight peptides
Energy balance

Aging

Levels fall with age
Longevity research
Healthy aging
Early human data

General science, not a promise of results. Your provider decides whether MOTS-c fits your plan.

Your plan

MOTS-c that fits
your week

Prescribed and dosed by a licensed provider
Guidance on movement, nutrition and sleep
Your dose reviewed as you respond
Questions answered by your care team

Talk to Our Team

A smiling mother carrying her young son on a sunny coastal trail

Build meals around protein, fiber and whole foods.Part of your metabolic plan

Real members

Care that adapts

Everyday wins

Personalized protocols

Push yourself further

Real members

Care that adapts

Everyday wins

Personalized protocols

Push yourself further

Real members

Care that adapts

Everyday wins

Personalized protocols

Push yourself further

MEMBER STORIES

Real people. Real protocols.

Coming Soon

The food noise went quiet by about week three. I stopped negotiating with myself at dinner and everything after got easier.

Rachel M.

The weight came off steadily instead of all at once, and my provider adjusted my dose whenever the loss started to stall.

Danielle P.

I am two sizes down and the clothes I had given up on fit again. None of it turned my week into a second full time job.

Marcus T.

I spent years stuck at the same number on the scale. It started moving in the first month and it has not gone back up yet.

Angela R.

I have kept the weight off for eight months now. It stopped feeling like willpower and started feeling like a normal day.

Priya S.

The food noise went quiet by about week three. I stopped negotiating with myself at dinner and everything after got easier.

Rachel M.

The weight came off steadily instead of all at once, and my provider adjusted my dose whenever the loss started to stall.

Danielle P.

I am two sizes down and the clothes I had given up on fit again. None of it turned my week into a second full time job.

Marcus T.

I spent years stuck at the same number on the scale. It started moving in the first month and it has not gone back up yet.

Angela R.

I have kept the weight off for eight months now. It stopped feeling like willpower and started feeling like a normal day.

Priya S.

The food noise went quiet by about week three. I stopped negotiating with myself at dinner and everything after got easier.

Rachel M.

The weight came off steadily instead of all at once, and my provider adjusted my dose whenever the loss started to stall.

Danielle P.

I am two sizes down and the clothes I had given up on fit again. None of it turned my week into a second full time job.

Marcus T.

I spent years stuck at the same number on the scale. It started moving in the first month and it has not gone back up yet.

Angela R.

I have kept the weight off for eight months now. It stopped feeling like willpower and started feeling like a normal day.

Priya S.

INSIDE THE PROTOCOL

Start low. Adjust often.

Semaglutide is not a fixed dose you take and hope for. You start low, step up on a schedule your provider sets, and hold wherever your body is responding well. That is the part most people never get, and it is the part that makes it liveable.

The weight kept coming off even when my provider held the dose steady. Nobody pushed me to the next number just to chase a faster result.

Dana K.

Semaglutide member, 7 months

GLP-1 weight loss

Your GLP-1 plan, handled end to end.

A licensed provider reviews your history, prescribes only if it is right for you, and adjusts as your body responds. Medication ships free, every month.

Coming Soon

✓

Licensed US providers, no clinic visits

✓

Free monthly shipping, cold packed

✓

No insurance required, cancel anytime

“Six months in and what surprises me most is how unremarkable it feels. No drama, no white knuckling, just steady.”

Dana K.

FAQ

Common
questions

What makes MOTS-c different as a mitochondrial peptide?

Nearly every peptide in your body is encoded by DNA in the cell nucleus. Mitochondria carry their own small genome, and only about eight peptides are known to come from it. MOTS-c is one of them.

Is MOTS-c related to NAD+?

Same neighborhood, different molecules. NAD+ is a coenzyme involved in energy metabolism. MOTS-c is a peptide your mitochondria make. They're talked about together because both center on the mitochondria.

Can I take MOTS-c with a GLP-1?

Both touch metabolism, which is why you want one provider looking at the whole picture instead of stacking on your own. If you're already with us, they can see what you're taking.

Do MOTS-c levels really drop as you age?

Circulating levels do fall with age. That's most of why MOTS-c is part of the longevity conversation, and your provider can explain what that means for you.

Is any of the MOTS-c research in people?

Some, and it's early. Most of the well known work is in mice and cell studies, which is why we don't promise results and your provider tracks how you respond.

Can I use MOTS-c if I'm a tested athlete?

No. MOTS-c is on the World Anti-Doping Agency prohibited list. If you're tested, check with your provider before starting anything.

MOTS-c (Injection)

From first question to front door.

From first question to front door.

Why choose Science & Co?