★★★★★

4.8 · 1,200+ member reviews

HSA & FSA eligible

Compounded Semaglutide (Injection)

A once weekly GLP-1 injection, prescribed by a licensed provider and built around your history, your goals and how your body actually responds.

Free overnight shipping

No insurance required

Plans from as low as $2 a day

Same Price, Any Dose

Get Started

Important safety information

Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. Prescription required.

Where does my Semaglutide come from?

A state licensed US compounding pharmacy prepares it for you, and every batch is third party tested for purity and potency. Compounded medications are not approved or evaluated by the FDA for safety, effectiveness or quality. Compounding pharmacies are licensed and inspected by state Boards of Pharmacy and are highly regulated. A prescription is required.

Does the price go up as my dose goes up?

No. You pay the same whether you are on your starting dose or your highest one. Plans start at $79 a month on the 12 month plan, which works out at about $2 a day. No hidden fees, no monthly membership, and free overnight shipping on every order.

What side effects should I expect?

Usually nausea, and usually early. Side effects most often show up in the first weeks after a dose increase and settle within a week or two. If they do not, message your care team and they will slow the climb rather than stop it. Always read the information supplied with your medication, and contact your provider about anything that concerns you.

How it works

From first question to front door.

What you get with Science & Co

A treatment plan with dose adjustments when clinically appropriate, a quick online assessment reviewed by a licensed provider, secure messaging and scheduled check ins with your care team, and medication shipped cold packed to your door. Every plan includes supplies, shipping and ongoing clinical monitoring.

How to take it

A once weekly injection you give yourself, on the same day each week unless your provider tells you otherwise. You start low and step up on a set schedule, which gives your body time to adjust and keeps side effects manageable.

Potential side effects

The most common side effects are nausea, constipation and diarrhoea, and they usually settle as your body adjusts to each step up in dose. Your provider reviews how you are doing at every check in and can slow the schedule down if you need it.

How does Science & Co ensure quality and safety?

We work only with state licensed US compounding pharmacies. Every batch is third party tested for purity and potency, and you can request a Certificate of Analysis for your prescription at any time.

How it works

From first question to front door.

Four steps from your first question to your first delivery. No clinic visit, no insurance required.

Get Started

Member completing the Science and Co online health questionnaire

Step 01

Take the quiz

A few questions about your health history, medications and goals. Five minutes, all online.

Step 02

Provider review

A US licensed provider reads your history and prescribes only if it is right for you.

Science and Co medication shipment being unboxed at home

Step 03

Free delivery

Prepared by a licensed US pharmacy and shipped free to your door, cold packed when needed.

Member messaging the Science and Co care team from a phone

Step 04

24/7 support

Message your care team any time, with regular check ins and dose adjustments as you go.

Weight loss, backed by science

Get Started

L→M

Drop a clothing size

Most members drop at least one size in their first months.

222 lbs→189 lbs

15% lost on average

Steady, provider guided progress you can track month to month.

Hungry→Satisfied

Reduce your cravings

The food noise quiets down, so choices get easier.

Drained→Energized

Get back your energy

Members report steadier energy through the whole day.

Illustrative outcomes. Individual results vary.

BEFORE

AFTER

See what's realistic for you.

Set your current weight for a rough estimate based on average results. It is a starting point, not a prediction. Your provider reviews your history and sets the actual plan with you.

Your current weight:

Weight (lbs)

You could lose:

47 lbs

This calculator provides an estimate only and is not a prediction of your individual results. Actual weight loss depends on multiple clinical factors and is determined in consultation with your healthcare provider.

US-Certified Pharmacy

Personal Treatments

Trusted by 125k+ Americans

1:1 Medical Support

Transparency

Why Science

You are trusting us with your health, and then trusting whatever shows up at your door. So the parts you cannot see are the parts we talk about most. Here is who writes your prescription, where your medication comes from, and who is there when you need them.

A real provider, every time.

Every prescription is written by a provider licensed in your state, after they read your health history.

US pharmacies only.

Your treatment

Semaglutide

Sealed by a licensed US pharmacy

Your medication is prepared and sealed by licensed US pharmacies. Nothing comes from overseas.

Someone to ask, always.

Care team

Hi, how can we help today?

Message your care team any time. Real answers from real people, with check ins and dose changes as you go.

Real members

Care that adapts

Everyday wins

Personalized protocols

Push yourself further

Real members

Care that adapts

Everyday wins

Personalized protocols

Push yourself further

Real members

Care that adapts

Everyday wins

Personalized protocols

Push yourself further

MEMBER STORIES

Real people. Real protocols.

Get Started

The food noise went quiet by about week three. I stopped negotiating with myself at dinner and everything after got easier.

Rachel M.

The weight came off steadily instead of all at once, and my provider adjusted my dose whenever the loss started to stall.

Danielle P.

I am two sizes down and the clothes I had given up on fit again. None of it turned my week into a second full time job.

Marcus T.

I spent years stuck at the same number on the scale. It started moving in the first month and it has not gone back up yet.

Angela R.

I have kept the weight off for eight months now. It stopped feeling like willpower and started feeling like a normal day.

Priya S.

The food noise went quiet by about week three. I stopped negotiating with myself at dinner and everything after got easier.

Rachel M.

The weight came off steadily instead of all at once, and my provider adjusted my dose whenever the loss started to stall.

Danielle P.

I am two sizes down and the clothes I had given up on fit again. None of it turned my week into a second full time job.

Marcus T.

I spent years stuck at the same number on the scale. It started moving in the first month and it has not gone back up yet.

Angela R.

I have kept the weight off for eight months now. It stopped feeling like willpower and started feeling like a normal day.

Priya S.

The food noise went quiet by about week three. I stopped negotiating with myself at dinner and everything after got easier.

Rachel M.

The weight came off steadily instead of all at once, and my provider adjusted my dose whenever the loss started to stall.

Danielle P.

I am two sizes down and the clothes I had given up on fit again. None of it turned my week into a second full time job.

Marcus T.

I spent years stuck at the same number on the scale. It started moving in the first month and it has not gone back up yet.

Angela R.

I have kept the weight off for eight months now. It stopped feeling like willpower and started feeling like a normal day.

Priya S.

MEMBER STORIES

Real people. Real protocols.

Get Started

BEFORE

AFTER

The food noise went quiet by about week three. I stopped negotiating with myself at dinner and everything after got easier.

Rachel M.

BEFORE

AFTER

The weight came off steadily instead of all at once, and my provider adjusted my dose whenever the loss started to stall.

Danielle P.

BEFORE

AFTER

I am two sizes down and the clothes I had given up on fit again. None of it turned my week into a second full time job.

Marcus T.

BEFORE

AFTER

I spent years stuck at the same number on the scale. It started moving in the first month and it has not gone back up yet.

Angela R.

BEFORE

AFTER

I have kept the weight off for eight months now. It stopped feeling like willpower and started feeling like a normal day.

Priya S.

BEFORE

AFTER

The first two weeks were harder than I expected and I nearly stopped. My provider adjusted the plan and it settled from there.

Simone W.

BEFORE

AFTER

I put it off for years because I did not want to sit in a waiting room. I started from my kitchen table on a Sunday.

Derek L.

BEFORE

AFTER

The scale is not the part I notice most. I get through the whole day now without hitting a wall at three o'clock.

Nicole B.

BEFORE

AFTER

The food noise went quiet by about week three. I stopped negotiating with myself at dinner and everything after got easier.

Rachel M.

BEFORE

AFTER

The weight came off steadily instead of all at once, and my provider adjusted my dose whenever the loss started to stall.

Danielle P.

BEFORE

AFTER

I am two sizes down and the clothes I had given up on fit again. None of it turned my week into a second full time job.

Marcus T.

BEFORE

AFTER

I spent years stuck at the same number on the scale. It started moving in the first month and it has not gone back up yet.

Angela R.

BEFORE

AFTER

I have kept the weight off for eight months now. It stopped feeling like willpower and started feeling like a normal day.

Priya S.

BEFORE

AFTER

The first two weeks were harder than I expected and I nearly stopped. My provider adjusted the plan and it settled from there.

Simone W.

BEFORE

AFTER

I put it off for years because I did not want to sit in a waiting room. I started from my kitchen table on a Sunday.

Derek L.

BEFORE

AFTER

The scale is not the part I notice most. I get through the whole day now without hitting a wall at three o'clock.

Nicole B.

BEFORE

AFTER

The food noise went quiet by about week three. I stopped negotiating with myself at dinner and everything after got easier.

Rachel M.

BEFORE

AFTER

The weight came off steadily instead of all at once, and my provider adjusted my dose whenever the loss started to stall.

Danielle P.

BEFORE

AFTER

I am two sizes down and the clothes I had given up on fit again. None of it turned my week into a second full time job.

Marcus T.

BEFORE

AFTER

I spent years stuck at the same number on the scale. It started moving in the first month and it has not gone back up yet.

Angela R.

BEFORE

AFTER

I have kept the weight off for eight months now. It stopped feeling like willpower and started feeling like a normal day.

Priya S.

BEFORE

AFTER

The first two weeks were harder than I expected and I nearly stopped. My provider adjusted the plan and it settled from there.

Simone W.

BEFORE

AFTER

I put it off for years because I did not want to sit in a waiting room. I started from my kitchen table on a Sunday.

Derek L.

BEFORE

AFTER

The scale is not the part I notice most. I get through the whole day now without hitting a wall at three o'clock.

Nicole B.

INSIDE THE PROTOCOL

Start low. Adjust often.

Semaglutide is not a fixed dose you take and hope for. You start low, step up on a schedule your provider sets, and hold wherever your body is responding well. That is the part most people never get, and it is the part that makes it liveable.

The weight kept coming off even when my provider held the dose steady. Nobody pushed me to the next number just to chase a faster result.

Dana K.

Semaglutide member, 7 months

GLP-1 weight loss

Your GLP-1 plan, handled end to end.

A licensed provider reviews your history, prescribes only if it is right for you, and adjusts as your body responds. Medication ships free, every month.

Get Started

✓

Licensed US providers, no clinic visits

✓

Free monthly shipping, cold packed

✓

No insurance required, cancel anytime

“Six months in and what surprises me most is how unremarkable it feels. No drama, no white knuckling, just steady.”

Dana K.

FAQ

Common
questions

How does Semaglutide work?

Three steps. Semaglutide mimics GLP-1, a hormone your body already makes after eating. It slows how quickly your stomach empties and quiets the appetite signals that keep you thinking about food, so you feel full sooner and stay full longer. It is prescribed alongside changes you make day to day, not instead of them.

What is the difference between Semaglutide and Tirzepatide?

One pathway versus two. Semaglutide acts on GLP-1. Tirzepatide acts on both GIP and GLP-1. Both are prescription injectables used for weight management, and which one suits you is a clinical decision your provider makes with you based on your history and your goals.

Do I need insurance to get started?

No. Science & Co is a cash pay service with transparent pricing, so there are no claims to file, no prior authorizations, and no surprise bills. Your plan covers the provider evaluation, your medication, and ongoing support.

Who prescribes my Semaglutide?

A licensed provider. Every prescription is written by a provider licensed in your state, after a real clinical review of the intake you complete. They stay available for follow up as your plan continues, and nothing is dispensed without their approval.

How long until I notice a change?

Appetite usually quietens first. Most people notice appetite changes within the first few weeks, usually before the scale moves. Because you start at a low dose and step up gradually, the early weeks are about tolerance rather than results. Your provider tracks how you are responding at each check in and adjusts from there.

Can I pause or cancel at any time?

Yes. There is no lock in and no cancellation fee. You can pause your plan if life gets in the way and pick it back up later, or cancel outright from your account.

Compounded Semaglutide (Injection)

From first question to front door.

From first question to front door.

See what's realistic for you.

Your current weight:

47 lbs

Why Science

Real people. Real protocols.

Real people. Real protocols.

Start low. Adjust often.

Your GLP-1 plan, handled end to end.

Common questions

Ready when you are.

Common
questions